There are several categories of PICOs. These categories tend to correspond with research designs. For example, therapy questions are usually answered with experimental designs, such as a randomized control trial.
Category |
Description |
Example PICO |
Commonly Associated Research Designs |
Therapy |
What is the effectiveness of a therapy, treatment, medication, or program?
|
In older adults in assisted living (P), is yoga (I) versus no yoga (C), helpful for decreasing stress and anxiety (O)? |
Experimental and quasi-experimental designs: RCTs. open label control trial. |
Diagnosis |
What is the best diagnostic tool for a given issue and population? |
For people exposed to COVID 19 but not experiencing symptoms (P), is the at home test 3EO Health COVID-19 (I) or the BinaxNOW COVID-19 Antigen Self Test (C) more accurate for diagnosing COVID 19 (O)? |
Cross sectional, case control and retrospective study designs. |
Prognosis |
What is likely to happen for patients with a given disease and condition and what might mitigate progression or symptoms? |
For women under 30 who have had breast cancer (P), and undergo a mastectomy (I), what is the likelihood of developing cancer again (O)? |
Longitudinal, cohort, prospective studies |
Harm |
What is the cause of a symptom or illness? |
Are young people (P) with a low fiber diet (I) compared with those with recommended fiber intake (C) at a higher risk for hypertension (O) before age 40? |
Longitudinal and retrospective studies |
Adapted from LoBiondo-Wood, G. & Haber, J. (2022). Nursing research: Methods and critical appraisal for evidence-based practice (10th ed.). Elsevier. pgs. 368-369.